Pestalotiopsis microspora

Porco, Jr. and coworkers also used this biomimehc domino approach for the synthesis of the quinone epoxide dimer torreyanic acid 7-151 as racemic mixture [67]. This natural product, isolated from the fungus Pestalotiopsis microspora, shows a pronounced cytoxicity to tumor cells. Its retrosynthetic analysis leads to the 2H-pyran 7-152 (Scheme 7.40). As substrate for the domino process, the epoxide... 

Metz AM et al., Induction of the sexual stage of Pestalotiopsis microspora, a taxol-producing fungus. Microbiology 146 2079—2089, 2000. 

Microbial transformation of ursolic acid (87) by the endophyte Pestalotiopsis microspora [82]. 

S.-B. Fu, J.-S. Yang, J.-L. Cui, Q.-F. Meng, X. Feng, D.-A. Sun, Multihydroxylation of ursolic acid by Pestalotiopsis microspora isolated from the medicinal plant Huperzia serrata, Fitoterapia 2011. 82, 1057-1061. 

Lee JC, Strobel GA, Lobkovsky E, Clardy JC. Torreyanic acid a selectively cytotoxic quinone dimer from the endophytic fungus Pestalotiopsis microspora. J. Org. Chem. 1996 61(10) 3232-3233. 

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