Perspectives on Multienzyme Process Technology

Cascade Biocatalysis Integrating Stereoselective and Environmentally VriendXy Reactions, First Edition. 

Edited by Sergio Riva and Wolf-Dieter Fessner. 

Reaction benefits Opportunity to create new pathways to products Pathways optimized toward product, minimizing by-products Opportunity to shift the equilibrium of a desired reaction by integrating in a cascade Secondary enzymes can be combined to assist primary reactions Potential solution for cofactor dependent reactions 

Biocatalyst benefits Dependent on format, downstream processes can be simplified Renewable catalyst Cells can be modified Enzymes can be designed 

Process benefits Flexibility for process control Reduced separation of intermediates Better reaction control Opportunities to exploit modeling and rapid development methods Novel reactor options Possible to run processes under more productive conditions (e.g., higher concentrations and organic solvents). Green processes running under mild conditions 

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