Peroxisome Proliferator-Activated Receptor y-Agonists and Stroke

8 Peroxisome Proliferator-Activated Receptor y-Agonists and Stroke 

The peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors of the nuclear hormone receptor superfamily. The three PPAR isoforms (a, p/8, and y) are known to occur in mammalian tissues. In response to specific agonists, these receptors form dimers and translocate to the nucleus, where they act as agonist-dependent transcription factors and regulate gene 

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