Perineal ischemia

Silva GV, Litovsky S, Assad JA, Sousa AL, Martin BJ, Vela D, Coulter SC, Lin J, Ober J, Vaughn WK, Branco RV, Oliveira EM, He R, Geng YJ, Willerson JT, Perin EC. Mesenchymal stem cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a canine chronic ischemia model. Circulation 2005 111 150-156. 

Perin EC, Dohmann Hp Borojevic R, et al, Improved exercise capacity and ischemia 6 and 12 months after transendocardial injection of autologous bone marrow mononuclear cells for ischemic cardiomyopathy. Circulation 2004 I 10 11213-11218. 

Perin, E.C., Dohmann, H.F., Borojevic, R., SUva, S.A., Sousa, A.L., Silva, G.V., et al. Improved exercise capacity and ischemia 6 and 12 months after transendocardial injection of autologous bone marrow mononuclear cells for ischemic cardiomyopathy. Circulation 110(11 Suppl. 1), II213-II218 (2004). doi 10.1161/01.CIR.0000138398. 77550.62... 

This situation is less common than low-flow priapism and can be classified as congenital due to arterial malformations, traumatic usually associated with penile, perineal or pelvic trauma, iatrogenic following revascularization procedures or idiopathic. The local blood gas tension in these patients is arterial, and therefore the penis is not at risk of ischemia and subsequent fibrosis. 

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