Peptic ulceration excessive acid secretion

It is conventional wisdom that excess acid is responsible for the formation of peptic ulcer, but acid, a normal constituent of gastric juice, is inadequate to produce a peptic ulcer. Most persons with duodenal ulcer have normal levels of acid secretion. As in most areas of medicine, the more we learn about some disease process, the more there is to learn.14... 

Because gastroenterologists believed that peptic ulceration is caused by excessive secretion of acid, they made innumerable studies of the rate of secretion of acid in the fasting state and in response to many forms of stimulation. By 1948 they began to wonder whether the capacity of the stomach to secrete depends upon the number... 

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