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Pepsin Metts

Boris Babkin inherited his interest in mucus from Pavlov, and he in turn encouraged his students to study the function of mucus. He also inherited from Pavlov s laboratory Mett s method for measuring pepsin. [Pg.118]

The esophagostomy ensured that no juice was contaminated with saliva. Babkin and Komarov measured the free and total acidity of a sample of gastric juice by titration and then added one or another preparation of alcohol-precipitated, dried hog gastric mucus. They placed Mett tubes in the mixture. After they had removed the tubes, Babkin and Komarov again determined the free and total acidity of the samples, but they did not measure the pH. According to their calculations, 330 mg of dried mucin did reduce the peptic power of the juice, and they concluded that mucus does indeed inhibit pepsin. ... [Pg.119]

Immediately after Popielski s discovery became known, Ernst Rothlin of Zurich began a series of experiments comparing the effects of subcutaneous injections of histamine with the response of a dog s Pavlov pouch to a meal. In a few instances, as for example on 3 April 1920, Rothlin found that the concentration of pepsin in juice, as measured by the Mett method, was as high in two samples obtained after histamine stimulation as in three samples obtained after the dog had eaten. Nevertheless, Rothlin concluded that histamine is a less potent stimulus of pepsin than of acid secretion. ... [Pg.161]

Pavlov, Work (n. 50), pp 28-29. There seems to be no accessible publication by Mett (or Mette) himself, but his method is described in detail in Samoilov A. Determination du pouvoir fermentative des liquides contenant de la pepsine. Arch Soc Biol St Petersboiirg 2 699-730, 1892. [Pg.365]


See other pages where Pepsin Metts is mentioned: [Pg.239]    [Pg.198]    [Pg.245]    [Pg.246]    [Pg.313]    [Pg.564]    [Pg.579]    [Pg.325]   
See also in sourсe #XX -- [ Pg.118 ]




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