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Pegademase bovine

Dosage form Adagen is a sterile solution, for injection. It is supplied in 1.5 ml single-dose vials. Each ml contains pegademase bovine 250 units. [Pg.258]

Pharmacokinetics Pegademase bovine is rapidly absorbed following intramuscular administration of Adagen, plasma adenosine deaminase activity generally normalizes after 2 to 3 weeks of weekly intramuscular injections. The half-life of pegademase is 48 to 72 hours. [Pg.259]

Adagen (pegademase bovine) [monomethoxy polyethylene glycol- Enzon Liquid pharmaceuti- (single use vial) cals 250 units/mL (pH 7.2-7.4) Isotonic solution IM... [Pg.308]

Oral 250 mg capsules 500 mg tablets 200 mg powder for suspension Parenteral 500 mg powder for injection Pegademase Bovine (Adagen)... [Pg.1361]

USA pegademase bovine enzyme Adagen Reaction product of recombinant adenosine deaminase with succinic anhydride and subsequent esterification with polyethylene glycol monomethyl ether Immuno- stimulant... [Pg.479]

Pegademase bovine for Severe combined immunodeficiency (SCID)... [Pg.524]

Pegademase bovine (Adagen) Enzon (1990) Adenosine deaminase SkDaPEG Severe combined immunodeficiency disease (SCED)... [Pg.49]

Pegademase bovine Severe combined immunodeficiency disease (SCID) Adagen Enzon Pharmaceuticals hic... [Pg.1707]

The ADA enzyme normally prevents the accumulation of toxic deoxy-ATP in cells. Deoxy-ATP is particularly toxic to lymphocytes, and leads to death of T and cells. Absence of the enzyme therefore results in SCID. Infusion of the purified enzyme (pegademase, from bovine sources) and transfer of ADA gene-modified lymphocytes have both been used successfully to treat this disease. [Pg.1189]

Parenteral 250 units/mL for IM injection Note Pegademase is bovine adenosine deaminase Pegaptanib (Macugen)... [Pg.1207]

See other pages where Pegademase bovine is mentioned: [Pg.595]    [Pg.618]    [Pg.596]    [Pg.620]    [Pg.258]    [Pg.258]    [Pg.500]    [Pg.556]    [Pg.1207]    [Pg.1422]    [Pg.215]    [Pg.1871]    [Pg.595]    [Pg.618]    [Pg.596]    [Pg.620]    [Pg.258]    [Pg.258]    [Pg.500]    [Pg.556]    [Pg.1207]    [Pg.1422]    [Pg.215]    [Pg.1871]    [Pg.1336]   
See also in sourсe #XX -- [ Pg.258 ]



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