Pediatric Pharmacology Research Unit Network

Marshall J, Rodarte A, Blumer J, Khoo KC, Akbari B, Kearns G. Pediatric pharmacodynamics of midazolam oral syrup. Pediatric Pharmacology Research Unit Network. J Clin Pharmacol 2000 40(6) 578-89. 

Pediatric Pharmacology Research Unit Network (2006). http //www.ppru.org/ (accessed January 2006). 

The Pediatric Pharmacology Research Unit (PPRU) is a network of experienced clinical investigators committed to facilitating pharmacological research in the pediatric medical community (55). Acting as a consortium, the PPRU has the potential to provide access to... 

The traditional PK study volunteer study in healthy children has proved very hard to set up, because of the attitude of many parents and overviewing independent review boards (IRBs). Even in pediatric patients, the frequency and total volume requirements for samples for conventional PK studies can cause the same refusals. However, there are pediatric research units that specialize in these studies, with minimum needle sticks, minute blood volumes and IRBs sympathetic to the needs of the pediatric community. The National Institute of Child Health and Human Development has set up a network of pediatric pharmacology units , usually in academic regional centers, now... 

---