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Pediatric patient epilepsy

Neuropsychiatric adverse events (3 to 12 years of age) Gabapentin use in pediatric patients with epilepsy 3 to 12 years of age is associated with the occurrence of CNS-related adverse events. [Pg.1254]

Because CBZ and valproate have been used for many years to treat seizure disorders in children and adolescents, more systematic knowledge about their clinical pharmacology in this age group is available than there is about lithium. However, pediatric patients with epilepsy are often on concomitant therapy with other anticonvulsants. That fact complicates attempts to extrapolate from this experience to the use of CBZ or valproate as monotherapy for childhood or adolescent bipolar disorder. For example, the risk of serious and potentially fatal hepatotoxicity with valproate occurs almost exclusively in children younger than age 10 years (usually 2 years or younger) who are on multiple anticonvulsants for congenital seizure disorders. How or whether this risk translates to children or adolescents who are on monotherapy with valproate for bipolar disorder is unknown. Nonetheless, clinicians need to be aware of this possible risk and take the following steps to increase the likelihood of early detection in case this problem arises ... [Pg.284]

Epilepsy, adjunctive therapy Adjunctive therapy for partial seizures in adults with epilepsy and as adjunctive therapy in the generalized seizures of Lennox-Gastaut syndrome in pediatric (at least 2 years of age) and adult patients. [Pg.1221]

Ueberall MA. Normal growth during lamotrigine monotherapy in pediatric epilepsy patients—a prospective evaluation of 103 children and adolescents. Epilepsy Res 2001 46(l) 63-7. [Pg.674]

Very few examples of outcomes research in neurological pharmacy exist. However, one historical control study determined that the implementation of a pharmacokinetics consultation service in an epilepsy clinic decreased seizure frequency and number of adverse effects compared with the baseline frequency in the 4 months prior to offering the service.A second study conducted in the pediatric epilepsy population described the effect of establishment of a specialty pediatric epilepsy clinic with clinical pharmacy services. Compared with patients seen before the beginning of the clinic, patients seen in the specialty clinic had decreased numbers of antiepileptic drugs and decreased doses of these medications. Frequency of seizures was not examined in this report. [Pg.589]


See other pages where Pediatric patient epilepsy is mentioned: [Pg.1241]    [Pg.528]    [Pg.1028]    [Pg.100]    [Pg.316]    [Pg.284]    [Pg.379]    [Pg.360]    [Pg.198]   
See also in sourсe #XX -- [ Pg.458 ]




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