Pearson, George

Edwin M Kaiser William G Kenyon R A Klein C Konig A Paul Krapcho Stephen J Kuhn William C Kuryla Peter A Leermakers Robert L Letsinger Guy S Lougheed B J Magerlein R J L Martin John G Moefatt D Nasipuri George A Olah D E Pearson R J Petersen G Ploss J Posner A Rieche... 

F. Basolo and R. G. Pearson, Mechanismen in der Anorganischen Chemie, Georg Thieme Verlag, Stuttgart, 1973, pp. 26-28. 

Janus C, Pearson J, McLauiin J, Mathews PM, Jiang Y, Schmidt SD, Chishd MA, Home P, Heslm D, French J, Mount HTJ, Nixon RA, Mercken M, Bergeron C, Fraser PE, George-Hyslop P, Westaway D (2000) A p peptide immunization reduces behavioral impauTnent and plaques in a model of Alzheimer s disease. Nature 408 979—982. 

Oliver Grummitt Charles R Hauser Charles D. Hurd Roland N. Icke E C. Korneeld H. F. McShane Sally Mickey C Miesse Charles S. Miller Irwin A Pearl D. E Pearson W P. Ratchfoed C. E Redemann C. T Redemann C. E Rehberg George A. Reynolds J. H. Saunders... 

Submitted bt George B. Kauffman and Llotd T. Taxahashi Checked by Karl H. PEARsoN,t Lewis W. SEQUiN,t and Stanley KlBSCHNERt... 

Table 5.19 lists the 21 QSARs that only used the Pearson and Mawby softness parameter (Op) to predict cation toxicity. Two of these QSARs are duplicates. The Turner et al. (1983) QSAR with r =0.360 is a duplicate of the Williams et al. (1982) QSAR with the same r value. The Turner et al. (1985) QSAR with r =0.879 is a duplicate of the Turner et al. (1983) QSAR with the same r value. The Jones and Vaughn (1978) QSAR for Ag+, Am, Cd " and Hg had the highest perhaps because of their proximity in the periodic table. The Turner et al. (1983) QSAR for Mn +, cm+, Ni +, Cu +, zm+, Cd +, Hg +and Pb " had the second highest r, perhaps because Mn +, Co +, NE+, and Zn " were in row 4 of the periodic table and Cd +, Hg + and Pm+ were in close proximity. For the Jones and Vaughn (1978) and Turner et al. (1983) references with 4 and 3 QSARs, respectively, the r decreased as the number of divalent cations increased (Table 5.18). The Babich et al. (1986) and Magwood and George (1996) QSARs both had high r and almost identical cations. The Babich et al. (1986) QSAR had almost identical cations to those used for the Turner et al. (1983) QSAR with r =0.879 (Table 5.18). The Enache et al. (1999) QSAR also had a high r. However, the Mendes et al. (2010) QSAR with a high r was the best for the highest number (18) of cations (Table 5.19).

Bergman s affinity tables took on their own ghostly afterlife well into the 19th century, long after the chemical revolution. The post-Lavoisierian British chemist George Pearson (a student of Joseph Black, himself a student of William Cullen) amended and extended Bergman s table to take account of the new chemistry... 

George Pearson (Rotherham, 1751-London, 9 November 1828), a pupil of Black, M.D. Edinburgh 1773, F.R.S. 1791, also studied in France, Germany, and Holland, practised as a physician in Doncaster and London, and became head-physician in St. George s Hospital, London. Pearson was one of the first to accept the antiphlogistic theory, and translated the Nomenclature Chimique in 1794 (see p. 481). He introduced the use of sodium phosphate in medicine in 1787. He prepared it from phosphoric acid made from phosphorus and nitric acid, and sold it at what he considered the low price of is. per lb. He investigated James s powder, an Indian wax resembling Chinese pe-la (tree wax) and Indian wootz steel. He analysed ancient copper, iron, etc. 

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