Pathogen-mimicking

P. Elamanchili et al, "Pathogen-mimicking" nanoparticles for vaccine delivery to dendritic cells. Journal of Immunotherapy, 30(4), 378 (2007). 

Most, and possibly all of these changes result from the tissue accumulation of phytanic acid. Phytanic is of dietary origin exclusively, and dietary restriction of phytanic and plasmapheresis are of clinical benefit. The defective gene and pathogenic mutations have been identified. The clinical manifestations can also be mimicked by defects of PEX7. 

Mimicking natural infection, live attenuated vaccines often generate long-lasting immunity against the pathogen. Because antigens are presented as replication-... 

Song, J. Cheng, Q. Zhu, S. Stevens, R. C. Smart materials for biosensing devices cell-mimicking supramolecular assemblies and colorimetric detection of pathogenic agents. Biomed. Microdevices 2002, 3, 213-221. 

Hoffman s group has dedicated great efforts to obtain new delivery systems to efficiently introduce biomolecules to intracellular targets (Henry et al., 2006 Pack et al., 2005). They mimicked the molecular machine of some viruses and pathogens that are able to sense the lowered pH gradient of the endosomal compartment and become activated to destabilize the endo-somal membrane. This mechanism enhances protein or DNA transport to the cytoplasm from intracellular compartments such as endosome. 

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