Particulate Dispersion Test Procedure

The purpose is to verify the parallelism of airflow throughout the work zone and the capability of the cleanroom to limit the dispersion. 

It is the responsibility of validation team members to follow the procedures. The quality assurance (QA) manager is responsible for SOP compliance. 

Visual smoke generator Particle counter Anemometer 

Divide the work zone into 2 X 2 ft equal areas. 

Set up the smoke generator, with outlet tube pointing in the direction of airflow and located at the center of a grid area at the work zone entrance plane. 

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Dispersant Activity Tests were conducted utilizing iron oxide and clay suspensions in order to establish the efficacy of the copolymers as dispersants for suspended particulate matter. Kaolin clay was used for the clay dispersion study. According to the procedure, separate 0.1% iron oxides and 0.1% clay suspensions in... 

SatnpCe Preparation. Seventy grams of sample, previously calcined at 538°C, was dispersed in about 125 mL of sodium metaphosphate solution and "wet screened" using a sieve stack of 250, 270 and 325 mesh, 8-inch diameter sieves. The sieves were washed with water until the effluent was free of any particulate and then rinsed with acetone to de-water. After air drying, the contents of each sieve were transferred to a porcelain dish and the material was recalcined at 538°C. Appropriate weights taken during this procedure allowed for the determination of percent moisture in the starting material and sieve analysis relative to the appropriate sieve fractions. The total +325 mesh material was recombined and mixed for the test. 

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