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Parasitic diseases kinetoplastids

Chagas disease is caused by a kinetoplastid trypanosoma parasite and affects millions of people in Latin America. The disease is currently incurable. Chemotherapy is based mainly on nitrofuran and nitroimidazole compounds and sterol biosynthesis inhibitors such as ketoconazole (337). Toxicity and high doses are the major problems for these organic drugs. Urbina et al. (338, 339) have found that com-plexation of antiparasitic organic agents such as chloroquine (78)... [Pg.241]

See other pages where Parasitic diseases kinetoplastids is mentioned: [Pg.103]    [Pg.164]    [Pg.165]    [Pg.278]    [Pg.291]    [Pg.264]    [Pg.1]    [Pg.33]    [Pg.33]    [Pg.81]    [Pg.81]    [Pg.85]    [Pg.87]    [Pg.42]   


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