Packaging rejects

Using this simplified model, CP simulations can be performed easily as a function of solution and such operating variables as pressure, temperature, and flow rate, usiag software packages such as Mathcad. Solution of the CP equation (eq. 8) along with the solution—diffusion transport equations (eqs. 5 and 6) allow the prediction of CP, rejection, and permeate flux as a function of the Reynolds number, Ke. To faciUtate these calculations, the foUowiag data and correlations can be used (/) for mass-transfer correlation, the Sherwood number, Sb, is defined as Sh = 0.04 S c , where Sc is the Schmidt... 

Air-cooled condensers require a large air flow for a given heat rejection duty and the limitation on their use is reached on account of their size and the need to get enough air. Water or evaporative cooling should always be considered as a possibility, except for smaller sizes or where using packaged condensing units. 

Modules Design-time units of development work Design decisions hidden in work units (packages) refinements used for submodule decompositions justifications, including rationale for choices made and choices rejected... 

Rejection of sodium sulphate was exceptional at the lower temperatures but permeate recovery was low. The testing at 81°C fulfilled Kvaerner s need to reduce overall skid costs and provide good rejection with an acceptable recovery rate. The use of high temperature membranes has provided the means to optimise the number of membrane elements, reduce the equipment costs and ensure that the SRS skid is an economically attractive package. 

For low-precision design the statistical package should include statistical rejection of outlying or aberrant observation. (EP makes no provision for this USP has a test — USP 24, standard deviation, regression analysis, and potency estimation.)... 

The cGMP regulations assign specific duties to the quality control unit. The unit is required to have the responsibility and authority to approve or reject all components, drug product containers, closures, in-process materials, packaging material,... 

One can use statistical software packages to calculate the level of control the process is under, and one may, for example, use process capability indices that compare the output of an in-control process to the specification limits. Indirect proxies for controllability metrics could also be the amount of materials and/or energy consumed per kg of product caused by excursions outside the control zone. For example, a rejected batch will become waste, and additional mass and energy will be required to replace or rework the rejected batch. 

Sealed pouches are then transported to the slitting and shear stations where each individual pouch is cut. The systems are then conveyed through an accept/ reject station where rejected material is discarded. The systems are sampled, tested, and released by the quality groups against preapproved product specifications. Upon quality control release, the individually pouched systems are collected for final packaging. This process is illustrated in Figure 8. 

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