P-Hederin

The Hederae folium trade sample 3 and commercial extrart 5 show low concentrations of saponin zones at Rf 0.2-0.3 and p-hederin at R, 0.75. The commercial extract 4 is prepared from Ptederae terrestris herba. 

Numerous triterpenoid saponins have been shown to inhibit pathogenic fungi, for example monodesmosides a and P hederin from the common ivy Hedera helix). Antifungal activity appears to be influenced by the number and kinds of sugar residues (Favel et al. 1994). 

Daston, G.P., G.J. Overmann, D. Baines, M.W. Taubeneck, L.D. Lehman-McKeeman, J.M. Rogers, and C.L. Keen. 1994. Altered Zn status by alpha-hederin in the pregnant rat and its relationship to adverse developmental outcome. Reprod. Toxicol. 8(l) 15-24. 

Shi, J.Z. and Liu, G.T. (1996) Effect of alpha-hederin and sapindoside B on hepatic microsomal cytochrome P-450 in mice. Acta Pharmacologica Sinica. 17, 264. 

Hederasaponins B, C, and D and a-, P- and y-hederin were extracted from leaves and baseline resolved on a C column (ELSD) using a 25-min 35/65 63 37... 

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