P Chlorobenzyl chloride

Reaction of chlorobenzene with p chlorobenzyl chloride and aluminum chloride gave a mixture of two products in good yield (76%) What were these two products ... 

Cm OROCARBONS AND Cm OROHYDROCARBONS - BENZYL Cm ORIDE, BENZAL Cm ORIDE AND BENZOTRICm ORIDE] (Vol 6) p-Chlorobenzyl chloride [104-83-6]... 

Chlorobenzyl chloride Ambenonium chloride Ticlopidine HCI p-Chlorobenzyl chloride Clobutinol Echonazole nitrate Indomethacin Pyrrobutamine Triparanol... 

Alkylation of the dianion of 3-bromophenylacetic acid (10) with p-chlorobenzyl chloride was accomplished using IiHMDS in THF to afford the substituted acid 11. The only significant impurity was the bis-alkylated product, which could be minimized by control of the reaction temperature to below -20 °C to give an 88%... 

Kinetics and Mechanism of Reactions of Bis (methyl-2,2 -dimercaptodiethyl-amine) dinickel(II) with Alkyl Halides. The rates of reaction of [Ni2 CH3N-(CH2CH2S)2 2], structure III, with methyl iodide, benzyl bromide, benzyl chloride, p-chlorobenzyl chloride, and p-nitrobenzyl chloride have been studied as functions of temperature and concentration in chloroform (3). Absorbance measurements were utilized to determine the rates. All experiments were conducted with excess alkyl halide (20 to 1000 times the initial concentration of complex). Jicha and Busch (18) were able to isolate alkylated complexes of the composition... 

All data obtained on the rate of reaction of [Ni(NiL2)2]Cl2 with alkyl halides— i.e., methyl iodide, benzyl bromide, benzyl chloride, p-nitrobenzyl chloride, p-chlorobenzyl chloride, ethyl bromide, ethyl iodide, n-propyl bromide, and n-propyl iodide—conform closely to a pseudo-first-order rate law. Almost all experiments were carried out in the presence of an excess of alkyl halide. Since methanol solutions of the alkylated complexes have only negligible absorption at 495 m//, rates were obtained by graphs of log A0—A vs. time. The graphs are linear over the entire time interval, which corresponds to more than two half lives in most cases, passing through the origin at zero time. The rate is essentially the same whether measured by the spectrophotometric or conductivity method. 

To a mixture of 100 ml of liquid ammonia and about 80 mg of black iron oxide was added 0.78 g (0.02 atom) of potassium. When all of the potassium had reacted, 3.3 g of N,N-dimethyl-N -(2-pyridyl)ethylenediamine was added. After the addition of 75 ml of dry toluene the ammonia was removed on the steam bath. To the cooled and stirred mixture was added 4.26 g of p-chlorobenzyl chloride, and the reaction mixture was stirred on the steam bath for 11 hours. It was then filtered and concentrated to an oil. This concentrate was taken up in ether, and the ethereal solution was washed with water, dried over sodium sulfate, and concentrated. Distillation gave 2.96 g of yellow liquid. Treatment of this distillate with an equivalent quantity of hydrogen chloride in absolute alcohol and precipitation by the addition of anhydrous ether gave 2.33 g of the N,N-dimethyl-N -(4-chlorobenzyl)-N -(2-pyridyl)ethylenediamine hydrochloride. 

In particular, minima in plots of AV against x2 are not necessarily due to the trend in the initial state quantity, and volumetric data can provide some indication of the details of reaction mechanism. Thus for the hydrolysis of p-chlorobenzyl chloride (Sn2), a shallow minimum in 5mAF for reaction in aqueous ethyl alcohol stems from a more intense maximum in 8m than for 5mF. At the other end of the scale, a sharp minimum in 8mAF for t-butyl chloride solvolysis (SnI) results from a sharp minimum in SmF, 5m V3 changing only gradually as x2 is increased. The behaviour of the volumetric properties for the benzyl... 

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