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Oxytocin side-chain conformations

In larger peptides such as oxytocin, analysis of side-chain conformation can be difficult because of the number of resonances involved. One approach to such a problem is to use lanthanide shift reagents. In the case of oxytocin, oxytocinoic acid, and tocinoic acid, it was shown that the presence of the... [Pg.295]

Our approach to testing this hypothesis and developing oxytocin antagonists with prolonged In vivo activity has been to further restrict the conformations of side chain groups at positions believed to be Important for binding In the antagonist... [Pg.19]

Deslauriers, R., 1. C. P. Smith, and R. Walter Conformational flexibility of the Neurohypophyseal Hormones oxytocin and Lysine-Vasopressin. A Carbon-13-Spin-Lattice Relaxation Study of back-bone and side chain. J. Amer. Chem. Soc. 96, 2289 (1974). [Pg.39]

See other pages where Oxytocin side-chain conformations is mentioned: [Pg.345]    [Pg.279]    [Pg.188]    [Pg.301]    [Pg.436]    [Pg.178]    [Pg.178]    [Pg.304]    [Pg.304]    [Pg.39]    [Pg.278]    [Pg.296]   
See also in sourсe #XX -- [ Pg.295 ]



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Chain conformation

Oxytocin

Oxytocin conformation

Oxytocine

Side-chain conformations

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