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Oxysterol-binding protein

Homolog of human oxysterol-binding protein (OSBP). [Pg.357]

Olkkonen, V.M. 2004. Oxysterol binding protein and its homologues new regulatory factors involved in lipid metabolism. Curr. Opin. Upidol. 15 321-327. [Pg.421]

Wangkanont, K. et aL (2011) Natural products reveal cancer cell dependence on oxysterol-binding proteins. Nature Chemical Biology, 7 (9), 639-647. [Pg.91]

The LDL receptor mechanism is only one way in which cells may regulate cholesterol formation. In particular oxidosterols derived from squalene-2,3 22,23-dioxide or from the cholesterol of LDL (via oxysterol binding protein) have been shown to inhibit HMG-CoA reductase effectively. The oxidosterols are present at high levels in LDL and may well account for some of the effects described in the LDL receptor mechanism. [Pg.332]

See other pages where Oxysterol-binding protein is mentioned: [Pg.98]    [Pg.335]    [Pg.17]    [Pg.871]    [Pg.872]    [Pg.380]    [Pg.380]    [Pg.418]    [Pg.420]    [Pg.477]    [Pg.478]    [Pg.483]    [Pg.591]    [Pg.871]    [Pg.872]    [Pg.374]    [Pg.374]    [Pg.376]    [Pg.320]    [Pg.81]    [Pg.247]    [Pg.112]    [Pg.112]   
See also in sourсe #XX -- [ Pg.418 ]



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