Oxygenases, properties

Marsho TV and Kung SD (1976). Oxygenase properties of crystallized fraction I protein from tobacco. Arch Biochem Biophys, 173, 341-346. 

Miziorko, H. M., and Lorimer, G. H., 1983. Ribnlose-l,5-bisphosphate car-boxylase/oxygenase. Annual Review of Biochemistry 52 507-535. An early review of die enzymological properties of rnbisco. 

Allen GC, Warren KD (1974) The Electronic Spectra of the Hexafluoro Complexes of the Second and Third Transition Series. 19 105-165 Alonso JA, Baibas LC (1993) Hardness of Metallic Clusters. 80 229-258 Alonso JA, Baibas LC (1987) Simple Density Functional Theory of the Electronegativity and Other Related Properties of Atoms and Ions. 66 41-78 Andersson LA, Dawson JH (1991) EXAFS Spectroscopy of Heme-Containing Oxygenases and Peroxidases. 74 1-40 Antanaitis BC, see Doi K (1988) 70 1-26... 

Gauthier JJ, SC Rittenberg (1971) The metabolism of nicotinic acid. I. Purification and properties of 2,5-dihydroxypyridine oxygenase from Pseudomonas putida N-9. J Biol Chem 246 3737-3742. 

Locher HH, T Leisinger, AM Cook (1991b) 4-Toluene sulfonate methyl monooxygenase from Comamonas testosteroni T-2 purification and some properties of the oxygenase component. J Bacteriol 173 3741-3748. 

Sparrow LG, PPK Ho, TK Sundaram, D Zach, EJ Nyns, EE Snell (1969) The bacterial oxidation of vitamin Bg. VII. Purification, properties, and mechanism of action of an oxygenase which cleaves the 3-hydroxypyridine ring. J Biol Chem 244 2590-2660. 

Ensley BD, DT Gibson (1983) Naphthalene dioxygenase purification and properties of a terminal oxygenase component. J Bacteriol 155 505-511. 

Block DW, F Lingens (1992b) Microbial metabolism of qninoline and related compounds XIV. Purification and properties of lH-3-hydroxy-4-oxoquinoline oxygenase, a new extradiol cleavage enzyme from Pseudomonas putida strain 33/1. Biol Chem Hoppe-Seyler 370 343-349. 

The following is review on the molecular and physical properties of this class of monooxygenases, which are also known as hydroxylases. A typical monooxygenase reaction is the hydroxylation of an alkane to an alcohol which involves a reduced cosubstrate that reduces a second atom within the O2 molecule to form water. Flavin-containing monooxygenases include lysine oxygenase and 4-hydroxybenzoate hydroxylase. Reduced pteri-dines are involved in the phenylalanine hydroxylase and tryptophan hydroxylase reactions. See also Cytochrome P-450... 

The main relevant characteristic properties of oxygenases are that they mostly involve transition metals (particularly iron and copper) as active centers and that they activate dioxygen and transfer it selectively to organic substrates. Oxygenases can be conveniently classified into two main families. 

Huner, N.P.A. Macdowall, F.D.H. (1979). The effects of low temperature acclimation on the catalytic properties of its ribulose bisphosphate carboxylase-oxygenase. Canadian Journal of Biochemistry 57, 1036-41. 

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