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Oxygen carrying retrievable nanoreactors

We have synthesized several kinds of retrievable nanoreactor materials for use as potential blood substitutes. Because of the large volumes needed clinically, and the rapid circuit time of blood in the body, continuous magnetic retrieval and immunoflltration are simple not practical methods for retrieval. Therefore, we focused on high buoyant density oxygen-carrying retrievable nanoreactors. Such materials could be separated in continuous fashion using clinically accepted aphaeresis units, cell savers and similar technologies. [Pg.521]

Fig. 15.1 shows a typical transmission electron microscopy image of Ca-P04-coated, oxygen-carrying, retrievable nanoreactors. Several variants of the calcium phosphate coating procedure can be employed to yield relatively uniformly coated particles 120-200 nm in diameter (Fig. 15.1). [Pg.522]


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