Oxygen binding by myoglobin

In order to study the function of oxygen binding by myoglobin and its effect on muscle function. Cole (Footnote 16) perfused an isolated muscle with hydrogen peroxide. Why did he do this ... 

Figure 7.6 Oxygen binding by myoglobin. Half the myoglobin molecules have bound oxygen when the oxygen partial pressure is 2 torr.

See also Oxygen Binding by Myoglobin, Oxygen Binding by Hemoglobin, Models of Allosteric Activity, Histidine... 

THE PHYSIOLOGICAL CHEMISTRY OF OXYGEN BINDING BY MYOGLOBIN AND HEMOGLOBIN... 

EXAMPLE 13.20 Type I muscle fibers are often referred to as red muscle fibers because they are colored a distinct reddish brown by their relatively large numbers of mitochondria that contain colored cytochromes in the electron transport chain (Chap. 10 Fig. 10-17). They are also characterized by their association with a dense blood supply and a high concentration of the red-colored oxygen-binding protein, myoglobin. On arrival of a nerve impulse, these cells contract relatively slowly, so they are often referred to as slow-twitch muscle fibers. Thus, type I fibers have evolved for slow, endurance contractions such as are used for maintaining posture. 

Myoglobin exists in the muscle cytosol and has a single oxygen-binding site. Myoglobin is a carrier in the facilitated transport of oxygen represented by the following reaction ... 

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