3-oxocyclohexyl phenyl

It has also been shown that dimethylsilyl enolates can be activated by diisopropylamine and water and exhibit a high reactivity toward iV-tosyl imines to give Mannich-type reaction products in the absence of a Fewis acid or a Bronsted acid.51 For example, the reaction of [(1-cyclohexen-l-yl)oxy]dimethylsilane with 4-methyl-A -(phenylmethylene)benzene sulfonamide gave re/-4-methyl-N- (f )-[(15)-(2-oxocyclohexyl)phenyl-methyl] benzenesulfonamide (anti-isomer) in 91% yield stereoselectively (99 1 anti syn) (Eq. 11.30). On the other hand, Fi and co-workers reported a ruthenium-catalyzed tandem olefin migration/aldol and Mannich-type reactions by reacting allyl alcohol and imine in protic solvents.52... 

Oxocyclohexyl)phenyl]propionic acid (4.0 g 16.2 mmoles) is dissolved in 1 N sodium hydroxide (55 ml) and treated with hydroxylamine hydrochloride (2.22 g 32 mmoles) during 24 h at room temperature. The gummy precipitate formed on acidification is converted to the sodium salt in aqueous solution which is then evaporated to dryness. The residue is dissolved in methanol or ethanol to remove an insoluble. After evaporating off the alcool, the sodium salt is again dissolved in water and converted to the acid which is crystallized from water-methanol (1 1), to give 3.0 g (yield 70%) of 2-[4-(3 -hydroxyimino-cyclohexyl)phenyl]propionic acid, melting point... 

Oxocyclopentyl and 3-oxocyclohexyl phenyl tellurium compounds reacted in tetrahydro-furan with butyraldehyde and benzaldehyde. The products of these aldol reactions were not isolated, but oxidized to the telluroxides that, in turn, were converted to enones by telluroxide elimination4. 

Copper-mediated addition of a functionalized alkylzinc iodide to an acid chloride preparation of 4-oxocyclohexyl 5-phenyl-5-oxopentanoate2... 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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