Oxidative Degradation of Hyaluronan

Before some basic reactions are discussed in more detail, one short definition of the terms free radicals and reactive oxygen species is needed [57] Basically, all free radicals are ROS , but not every ROS is a free radical . Free radicals are always paramagnetic compounds due to the presence of an 

The in vivo generation of all relevant species is discussed in the next paragraph, while some selected laboratory scale-methods to study ROS generation are also discussed. 

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