Overview of the Point Groups

Pharmaceutical cGMPs for the 21st Century was intended to enhance and modernize the regulation of pharmaceutical manufacturing and product quality. This report provides an overview of the PAT Team s and Manufacturing Science Working Group s collaborative efforts, accomplishments, and points to consider as the initiative moves into its next phase (implementation and continuous improvement). 

The data in Tables 1-3 probably constitute the most extensive overview available for solution M-H BDE data that have been obtained by a single method. The effect of ancillary ligands on the M-H BDEs in series of related complexes can be studied in some detail. It was pointed out in Section 3.3.1 that the BDEs are remarkably insensitive to certain changes in the ligands. For example, within each of the following groups from Table 1, BDE differences are smaller than 8 kJ moL CpCr(CO)2(L)H (entries 1-4) CpW(CO)2(L)H (entries 12 and 13) Mn(CO)4(L)H (entries 17 and 18) Co(CO)3(L)H (entries 24-26) CpM(CO)3H compared with Cp M(CO)3H (M = Cr, entries 1 and 5 Mo, entries 8 and 9). Similar effects are found in Table 2 less than 5 kJ mol differences within the series CpIr(CO)(L)H+ (entries 32-39) Cp Ir(COD)H+ (entries 41-45) Cp Ir(CO)(L)H+ (entries 46-51, where the dicarbonyl differs somewhat more from the substituted compounds). 

In this sections, we will present the overview of the natural nano-silicaties as advanced nanoarchitectures currently employed to transform solar into chemical energy. It should be pointed out that this section will emphasize the optimization of silicate-based photocatalysts under sunlight-type excitation operation both under UV and under visible light excitations are considered. In addition, our group s work will be exemplified to discuss the metal oxide-based minerals naturally contain doped transition metal ions isomorphically substituted into the structure that can alter the structural as well as electronic properties. 

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