Osteoclasts rabbit bones

The results of animal tests using rats, rabbits, and dogs have demonstrated high biocompatibility and high osteoconductivity. Moreover, the most impressive bone tissue reaction of the HAp/Col composites is incorporation of the composites into the bone-remodeling process, that is, they are resorbed by osteoclastic cells. ... 

Nacre has been tested in human, sheep, and rabbit models (Lamghari et al., 2001). In human patients, fresh woven bone bonds itself throughout the nacre implant, augmented by the heightened activities of osteoblasts and osteoclasts (Figure 1.8). While nacre is stably tolerated in vivo, its degradation and resorption is limited and this... 

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