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Orthoacetic acid trimethyl ester Diflorasone diacetate

The diflorasone is reacted with orthoacetic acid trimethyl ester in the presence of toluene sulfonic acid to give diflorasone diacetate. [Pg.487]

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3,3 - diacetic acid

Diflorasone diacetate

Orthoacetate

Orthoacetic acid trimethyl ester

Trimethyl orthoacetate

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