Ornithine Carbamoyl Transferase OCT

Inborn errors of the six enzymes of ureagenesis and NAG synthase have been described. The inheritance pattern of the last is not known, but five of the urea cycle defects are autosomal recessive and ornithine carbamoyl-transferase (OCT) deficiency is X-linked. 

Two of the urea cycle enzymes (Figures 3.2.and 3.5), which are located in the hepato-cytes and both ornithine carbamoyl transferase (OCT) and arginase can provide evidence of liver damage in animals, although more data are available for OCT (Cornelius... 

Brohult J. Effects of high protein and low protein diets on ornithine carbamoyl transferase activity in human serum (S-OCT). Acta Med Scand 1969 185 357-62. 

Figure 2.8. The urea cycle. CS = carbamoyl phosphate synthetase. OCT = ornithine carbamoyl transferase.. 45S = arginosuccinate synthetase. AS arginosuccinate. A = arginase...

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