Organotin toxicants, polymer supported

Since Pereyre and coworkers reported the catalytic activity of tributyltin alkoxide for transesterification reaction [87], organotin derivatives have been used for various kinds of organic transformations. Distannoxane compounds were found to play an important role in the reaction [88-90] and act as pure Lewis acid [91, 92]. Although the transesterification reactions proceeded by using low-molecular-weight catalyst in homogeneous medium, a serious drawback for the industrial processes is a removal of the toxic tin derivatives. In such cases the use of polymer-supported version... 

At the same time, there can be concerns about the disposal of organotin residues, and of traces of toxic organotin residues remaining in the products, and fluorous, polymer-bound, and solid-supported organotin compounds are being increasingly used to avoid the problem. 

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