Organogold compounds reactions

Organogallium compounds, 12 361 Organogermanium compounds, 12 554 Organogold compounds, 12 707-708 Organohalogen compounds (AOX), 26 398 Organohalogens, in Grignard reactions, 12 824... 

Stable Au intermediates have been identified in analogous reactions of organogold compounds. See ref. S3, p. 386, and refs, therein. 

The volume contains 16 chapters dealing with calculations on organogold compounds, physical and spectroscopic properties (NMR, ESR, PES, Mossbauer spectra), thermochemical and analytical properties, the synthesis and uses of the title compounds and their reactions such as rearrangements, pyrolysis and photochemical reactions. The medicinal use of organogold compounds and the increased use of gold-thiol monolayers are also summarized. 

Prior to these mechanistic findings by Nolan and coworkers, Hashmi and coworkers found very similar mechanistic principles in their studies of cyclization reactions of 1,5-diynes [31]. In these cyclization reactions, two gold atoms are also needed to dual activate the initial substrate (see Scheme 9.13). Further mechanistic studies also revealed the occurrence of a, in this case even isolable, ew-diarated species, which on their own can serve as catalysts for the studied reactions. These species therefore highlight the importance of organogold compounds. 

In analogy to other organogold compounds, the Au(I)-alkyne complexes can be synthesized starting from the NHC-Au(I)-chlorides through a transmetalla-tion reaction (see Scheme 9.15) [33]. 

The Hammond-type organogold compounds 19, even though not highly reactive toward electrophiles, can efficiently be used in cross-coupling chemistry (Scheme 4.7). This adds a new dimension to the synthetic potential and efficiency of the organic chemistry of gold [26]. Also, other organogold complexes could be used. Scheme 4.7 shows the catalytic cycle for these reactions, which form new C-C bonds. Initially, palladium(O) is formed by stoichiometric reduction of a stable palladium(II) catalyst precursor. The subsequent reaction is catalytic... 

The reaction with active methylene compounds results in the hydrogen abstraction to give the alcohol and the organogold derivatives.178... 

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