Organoarsenic compounds reaction with

Many organoarsenic compounds are prepared by reactions of AsC13 with alkyl group transfer agents such as Grignard reagents, lithium alkyls, or aluminum alkyls. Typical reactions include... 

Relatively few organoarsenic compounds that contain an As-B bond are known. > > In most cases, these are synthesized by the straightforward reaction of the primary, secondary, and tertiary arsine with diborane or BH3 THF (equation 29). As-B bonding also results when the BH3 moiety reacts with Sn-As and As-P-As bonded compounds (equations 30 and 31). ... 

The pyrolysis of organoarsenic compounds containing the arsenyl moiety has some limited preparative applications [arsenyl (As=0) by analogy with phosphoryl (P=0)]. The compounds are based on the arsonic acid RAs(0)(0H)2, the arsinic acid R2As(0)0H and the arsine oxide R3As=0 structures. The acids are in interesting contrast with the phosphorus series. The phosphonic and phosphinic esters are prepared from the phosphorus(III) precursors via the Arbuzov synthesis. This synthetic route fails with the arsenic analogues, and further, if an alkyl halide or a salt is added in the pyrolysis of arsonic or arsinic acid esters a retro-Arbuzov reaction takes place . ... 

The molecular characterization of methylarsonic acid, phenylarsonic acid and the inorganic anion, arsenate, found in a methanol extract of a Green River Formation Oil shale sample was accomplished by HPLC-GFAA analysis In addition, derivatization of the acids, HPLC purified, by reaction with 3-methylcatechol to form the five coordinate organoarsenic catecholates as well as reaction, via trimethylsilylation, of the ammonium salt of arsenate to form tristrimethylsilylarsenate was followed by GC-EIMS analysis to provide unequivocal evidence for the presence of these organometallic and inorganic compounds of arsenic as natural products in oil shale ... 

The use of derivatization methods for the analysis of organoarsenic compounds is suitable to generate GC-capable products, but changes significantly the composition of the sample. After derivatization it is often not possible to differentiate between compounds giving the same derivatization products. Furthermore it is necessary to pay attention on the influence of the matrix which interact the extraction and derivatization yield crucially. The further development in analysis of hydrophilic and non volatile organoarsenic compounds should thus include methods without any derivatization reactions like the direct measurement of water extracts using HPLC in combination with different detection principles. 

Reactions of organoarsenic compounds are summarized in Fig. 4.10. Alkyl-arsonic and dialkylarsinic acids can be prepared by the Meyer reaction. An alkyl halide or sulphate is treated with an alkali metal arsenite in aqueous solution. 

There is only one study that suggests the possible metabolic and detoxification fate of DM (Hass et al., 2004). As an organoarsenical compound, it would seem likely that its toxicity may be linked to tiie metabolism of arsenic. Through the oxidation of As (III) by manganese peroxide, DM is broken down into As (V). This reaction releases chloride with the subsequent incorporation of two oxygen molecules into the parent compound (Haas... 

Reaction of organoarsenic(V) halides or oxides with several nitrogen nucleophiles gives the corresponding nitrogen compounds. Several examples are shown in equations... 

Arsenic found in non olefinic liquid hydrocarbons is present as organoarsenic species and thus must be converted to a more reactive form to be efficiently trapped. This can be achieved using the single step process. Feedstock treatment with a metal sulfide containing catalyst adsorbent, under the appropriate reaction conditions permits the total conversion and trapping of arsenic compounds as shown in the following mechanism ... 

Bonds to Carbon.—Arsenic(ja) Compounds. Organoarsenic chemistry for 1971 has been reviewed. Methyldichloroarsine reacts with diazomethane to give the chloromethyl derivatives MeAs(CH2Cl)Cl and MeAs(CH2Cl)2, and the action of nucleophiles on these compounds is described. Ketoxime esters of benzenearsonous acid, PhAs(ON CR R )2, can be obtained by the reaction of PhAsO with ketoximes, while an alternative route from PhAsCl2 is also described. 

---