Organic-anion-transporting specificity

Abe, T., et al. Identification of a novel gene family encoding human liver-specific organic anion transporter LST-l.J. Biol. Chem. 1999, 274, 17159-17163. 

Nakai, D., et al. Human liver-specific organic anion transporter, LST-1, mediates uptake of pravastatin by human hepatocytes. J. Pharmacol. Exp. Ther. 2001, 297, 861-867. 

Abe, T., Kakyo, M., Tokui, T., Nakagomi, R., Nishio, T., Nakai, D., Nomura, H., Unno, M., Suzuki, M., Naitoh, T., Matsuno, S., Yawo, H., Identification of a novel gene family encoding human liver-specific organic anion transporter 1 ST-1, /. Biol. Chem. 1999, 274, 17159-17163. 

P. J., Hagenbuch, B., Localization of organic anion transporting polypeptide 4 (Oatp4) in rat liver and comparison of its substrate specificity with Oatpl, Oatp2 and Oatp3, Pfliigers Arch. 2001, 443, 188-195. 

Tamai, I., Nozawa, T., Koshida, M., Nezu, J., Sai, Y., Tsuji, A., Functional characterization of human organic anion transporting polypeptide B (OATP-B) in comparison with liver-specific OATP-C, Pharm. Res. 2001, 18, 1262-1269. 

Bossuyt X, Muller M, Meier PJ. Multi-specific amphipathic substrate transport by an organic anion transporter of human liver. J Hepatol 1996 25(5)733-738. 

Abe T, Unno M, Onogawa T, Tokui T, Kondo TN, Nakagomi R et al. Lst-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers. Gastroenterology 2001 120(7) 1689—1699. 

Wijnholds J, Mol CA, van Deemter L, de Haas M, Scheffer GL, Baas F et al. Multidrug-resistance protein 5 is a multi-specific organic anion transporter able to transport nucleotide analogs. Proc Natl Acad Sci USA 2000 97( 13) 7476-7481. 

Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters. The Journal of Biological Chemistry, 274, 37161-37168. 

D. Sugiyama, H. Kusuhara, H. Taniguchi, S. Ishikawa, Y. Nozaki, H. Aburatani, and Y. Sugiyama. Functional characterization of rat brain-specific organic anion transporter (Oatpl4) at the blood-brain barrier High affinity transporter for thyroxine. J. Biol. Chem. 278 43489-43495 (2003). 

Suzuki T, Onogawa T, Asano N, Mizutamari H, Mikkaichi T, Tanemoto M, Abe M, Satoh F, Unno M, Nunoki K, Suzuki M, Hishinumo T, Goto J, Shimosegawa T, Matsuno S, Ito S, Abe T. Identification and characterization of novel rat and human gonad specific organic anion transporters. Mol Endocrinol 2003 17 1203-1215. 

Cattori V, Hagenbuch B, Hagenbuch N, et al. Identification of organic anion transporting polypeptide 4 (Oatp4) as a major full-length isoform of the liver-specific transporter-1 (rlst-1) in rat liver. FEBS Lett 2000 474 242-245. 

Kakyo M, Unno M, Tokui T, et al. Molecular characterization and functional regulation of a novel rat liver-specific organic anion transporter rlst-1. Gastroenterology 1999 117 770-775. 

Buist SC, Cherrington NJ, Choudhuri S, et al. Gender-specific and developmental influences on the expression of rat organic anion transporters. J Pharmacol Exp Ther 2002 301 145-151. 

Kusuhara H, Suzuki H, Sugiyama Y. The role of P-glycoprotein and canalicular multi specific organic anion transporter in the hepatobiliary excretion of chugs. J Pharm Sci 1998 87 1025-1040. 

Ohtsuka H, Abe T, Onogawa T, et al. Famesoid X receptor, hepatocyte nuclear factors lalpha and 3beta are essential for transcriptional activation of the liver-specific organic anion transporter-2 gene. J Gastroenterol 2006 41 369-377. 

---