Oral chemosensory receptor

Figure 3. Location of some oral chemosensory receptor systems. Taste buds (schematic upper right) are found on specialized papillae on the tongue and scattered on the palate and posterior oral structures. Free nerve endings are found...

Long-chain fatty acids such as stearic acid or linoleic acid may activate signaling systems in the oral cavity, intestines, and CNS of rodents [42, 43]. Based on animal studies, several mechanisms have been proposed for chemosensory transduction of long-chain fatty acids in the oral cavity. One mechanism involves the inhibition of a delayed rectifying channel by long-chain fatty acids in isolated taste receptor cells [44,45]. 

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