Open Mass Spectrometry Search

Geer LY, Markey SP, Kowalak JA, et al. Open mass spectrometry search algorithm. J Proteome Res. 2004 3 958-64. doi 10.1021/pr0499491. 

J. Proton Affinity Retrieval Prograno. With the current high level of interest in chemical ionization mass spectrometry, there is a need for a reliable file of gas phase proton affinities. No data base of this sort has previously been assembled and for these reasons, the task of gathering and evaluating all published gas phase proton affinities has been undertaken by Rosenstock and co-workers at NBS. This file [28], which has about 400 critically evaluated gas phase proton affinities drawn from the open literature, and can be searched on the basis of compound type or the proton affinity value. It will be appended to the MSSS and the bibliographic component will be merged with the Mass Spectrometry Bulletin Search System. 

C. D. Wagner, J. T. Hall, K. A. Hoffman, W. L. White, and J. D. Williams, Open-access mass spectrometry utilizing advanced protein search processing integrated with a multi-site protein analysis LIMS, in 52nd ASMS Conference on Mass Spectrometry and Allied Topics, Nashville, TN (Book of Abstracts), 2004. 

One of the most important applications of mass spectrometry has always been the determination of molecular mass. Since this can be difficult with EIMS, the search for soft ionization techniques is almost as old as organic mass spectrometry. The first step was chemical ionization and particularly direct chemical ionization (DCl), which allowed the samples to be desorbed directly from a thin wire into the Cl plasma. It has been successfully u,sed for natural compounds such as glycerides. Later, field ionization (FI) and especially field desorption (FD) opened up new possibilities for the analysis of labile natural compounds such as saccharides, fteptides, and nucleotides. When fast... 

---