Olivin synthesis

A similar synthetic strategy was applied in the synthesis of menogaril 83, another important anthracycline antitumour antibiotic, and to the synthesis of the tricyclic core of olivin 87, the aglycon of the antitumour antibiotic olivomycin [61,62]. In both cases a tandem benzannulation/Friedel-Crafts cyclisation sequence yielded the tetracyclic and tricyclic carbon core, respectively (Scheme 42). 

Scheme 42 Studies towards the synthesis of menogaril and olivin...

Scheme 6.10. Stereoselective cuprate addition to enal 61 the key step to A/ards the synthesis of olivin. (TBS = t-butyidimethylsilyl, TMS = trimethylsilyl)...

The synthesis of olivin was recently completed in our laboratories at Indiana University using homoallyl alcohol 15 as a key intermediate. It is beyond the scope of this presentation, however, for us to discuss this synthesis in detail here. For now, therefore, we leave the topic of olivin and consider instead additional applications of allylboronates in the synthesis of carbohydrates and other polyoxygenated materials. 

The method was used for oxidation of an unsaturated nitrile (1) to an aromatic acyloin (2) in a projected synthesis of a model for olivin (4), an aglycone of olivomycin antibiotics.2... 

An answer to the first question was suggested by Lancet and Anders (1970). The principal meteoritic phases stable above 350-400 K (olivine, pyroxene, Fe, FeS) are not effective catalysts for the Fischer-Tropsch reaction, whereas the phases forming below this temperature (hydrated silicates, magnetite) are. P hough metallic iron is often regarded as a catalyst for this synthesis, the catalytically active phase actually is a thin coating of FCjO formed on the surface of the metal (Anderson, 1956)]. Thus CO may have survived metastably until catalysts became available by reactions such as ... 

Franck, R W, Bhat, V, Subramanian, C S, Stereoselective total synthesis of the natural enantiomer of olivin trimethyl ether, J. Am. Chem. Soc., 108, 2455-2457, 1986. 

In their synthesis of olivin, the aglycon segment of olivomycin A, Roush and coworkers used a highly diastereoselective substrate-directed y-alkoxy allylation reaction to set the C(l ) stereocenter [80]. Thus, reaction of the aldehyde 90, derived from L-threonine, with the [(Z)-y-methoxyallyl]boronate 91 resulted in the highly diastereoselective formation of adduct 92. The stereochemistry of 92 is consistent... 

Liptak, V.P., and Wulff, W.D., The preparation and evaluation of electron poor henzylidene Fischer carbene complexes. Studies toward the total synthesis of (+)-olivin. Tetrahedron, 56, 10229, 2000. 

SYNTHESIS OF OLIVINE (LiFeP04> and Ni/OLIVINE (LiFeP04) CATALYSTS FOR UPGRADING SYN-GAS PRODUCTION... 

Synthesis of Olivine (LiFeP04) and Ni/Olivine (LiFeP04) Catalysts... 

The aim of this paper is to show that olivine can be an interesting support for nickel, giving a system with high attrition resistance and strong linking with nickel. The present work showed the synthesis of olivine support and its evolution with calcinations temperature. The nickel/olivine catalyst was then synthesized via impregnation method. 

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