Oligostilbenes naturally occurring

ABSTRACT More than 200 naturally occurring oligostilbenes isolated from plant kingdom are grouped into I-V structural types. They are a special kind of polyphenolic natural products with multi-faceted bioactivities. This article will review their classification, distribution, spectral characteristics, biological activities (anti-fungal, antibacterial, antioxidant, anti-inflammatory and anticarcinogenic activities, etc.) and mimetic biosynthesis. 

Most naturally occurring oligostilbenes belong to this type and are further divided into four groups (I-A, I-B, I-C and I-D) according to whether they contain oxa-cyclic rings and the type of polymerization. 

The structural elucidation of naturally occurring oligostilbenes depends on a modern spectroscopic evidence, such as MS, NMR, IR and UV. All kinds of 2D-NMR techniques (including COSY, HMQC, HMBC, NOESY) play important roles in the structural elucidation of oligostilbenes. We will mainly summarize their 1H NMR and l3C NMR characteristics in this section. 

Most naturally occurring oligostilbenes have been isolated as amorphous powder, therefore it was very difficult to determine their structures by... 

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