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Oligosaccharides block synthesis, thioglycosides

The synthesis is an excellent example of the use of thioglycosides as glycosyl donors in the block synthesis of complex oligosaccharides as well as the use of partial glycosylation of diols to achieve short paths to the target. [Pg.195]

Included are two examples of the two- and three-step sequential oligosaccharide assembly to illustrate Approach A. The first synthesis makes use of trichloroacetimidate 239, which is selectively activated over the thioglycoside acceptor 240 with TMSOTf (Scheme 49). The SPh moiety of the resulting tetrasaccharide is then activated over the added glycosyl acceptor 241 by addition of NIS and TfOH to provide hexasaccharide 242 in 50% yield over two steps.100 This approach combines advantages of the selective activation, convergent block strategy, and one-pot synthesis. [Pg.216]

See other pages where Oligosaccharides block synthesis, thioglycosides is mentioned: [Pg.179]    [Pg.180]    [Pg.191]    [Pg.200]    [Pg.491]    [Pg.100]    [Pg.122]    [Pg.212]    [Pg.88]    [Pg.618]    [Pg.19]    [Pg.222]    [Pg.222]    [Pg.98]    [Pg.187]    [Pg.205]    [Pg.293]    [Pg.99]    [Pg.104]    [Pg.8]    [Pg.44]    [Pg.229]    [Pg.185]    [Pg.109]    [Pg.24]    [Pg.197]    [Pg.199]    [Pg.39]    [Pg.44]    [Pg.620]    [Pg.623]    [Pg.743]    [Pg.664]    [Pg.1233]    [Pg.167]    [Pg.201]    [Pg.733]    [Pg.58]    [Pg.336]    [Pg.608]    [Pg.610]    [Pg.15]    [Pg.15]    [Pg.23]    [Pg.31]    [Pg.222]    [Pg.437]   
See also in sourсe #XX -- [ Pg.52 , Pg.191 , Pg.192 , Pg.193 , Pg.194 , Pg.195 , Pg.196 , Pg.197 ]



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1-Thioglycosides

Block synthesis

Block synthesis, oligosaccharides

Thioglycoside

Thioglycoside synthesis

Thioglycosides block syntheses

Thioglycosides synthesis

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