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Oligosaccharide solid-phase synthesis cleavage conditions

Solid-phase Oligosaccharide Synthesis. Methanesulfonyl chloride resin 1 was used as an activating linker in the synthesis of various polymer-bound di and trisaccharides 2 (eq 1). The sulfonate linker proved stable to glycosidation and alcohol deprotection conditions, and nucleophilic displacement of 2 by Nal provided 6-iodosaccharides (eq 1). NaOAc and NaNs were also suitable nucleophiles for cleavage of the sulfonate linker. ... [Pg.545]


See other pages where Oligosaccharide solid-phase synthesis cleavage conditions is mentioned: [Pg.11]    [Pg.79]    [Pg.105]    [Pg.137]    [Pg.321]    [Pg.41]    [Pg.383]    [Pg.490]    [Pg.101]    [Pg.4]    [Pg.69]    [Pg.113]    [Pg.224]    [Pg.229]    [Pg.263]   
See also in sourсe #XX -- [ Pg.241 , Pg.247 ]




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