Oleuropein aglycone

The first NMR study of olive oil components appeared in 1993 by the Montedoro group (Montedoro et ah, 1993), in which three extracted poly-phenolic compounds (one isomer of oleuropein aglycone, the dialdehydic... 

Fig. (2). Structure of the dialdehydic forms of elenolic acid linked to (3,4-dihydroxyphenyl)-ethanol (compound 1) and to (p-hydroxyphenyl)-ethanol (compound 2). Compound 3 is an isomer of oleuropein aglycone.

A good correlation (r = 0.97) was foimd with the dialdehydic form of hydroxytyrosol-elenolic acid and the isomer of oleuropein aglycone (compounds 1 and 3). a -Tocopherol acted synergically with hydrox5dyrosol and the secoiridoid derivatives [45,46]. Sunlight exposure... 

Oenanthe javanica (Japanese Parsley) (Falcarindiol) Olive oil Oleocanthal Oleuropein aglycone Orcein... 

Oleuropein. Transgenic AD mice supplemented with oleuropein aglycone (50 mg/kg of diet), the main polyphenol found in extra virgin olive oil, showed improvement in cognitive performance, reduced p-amyloid levels and plaque deposits, and an intense autophagic reaction [228]. 

Demethyl oleuropein aglycon rapidly eliminated the carboxyl group, giving 29. 

Figure 18 shows compounds that are transferred in the oil. Some people insists on searching oleuropein in the oil, cutting of compounds that are more abundant, thinking that oil preparation should be a simple transfer of compounds from olive to oil, instead of a complex series of enzymatic and non-enzymatic reactions. The presence of the various forms of oleuropein aglycon was demonstrated by their isolation from olive oil [42- 43, 23]. 

Hydroxy-tyrosol (DPE 3,4-dihydroxyphenylethanol) is a liposoluble and hydrosoluble compound present in high concentration in extra virgin olive oil, in free or esterified form, such as oleuropein aglycone [42-43]. 

The obtained data revealed, first of all, the high ease of use of DPE and the relationship between nutritional positive effects of olive oil and the high content of DPE and its precursor, oleuropein aglycone [71],... 

LLE (olive oil) SEE (olive oil) Tyrosol, hydroxytyrosol, vanillic acid, deacetoxy-oleuropein aglycon, pinoresinol, and acetoxypinoresinol UV (280/200 nm) HPLC-MSD CZE-HPLC... 

Anti-inflammatory antioxidant oleuropein oleuropein aglycones... 

Caruso D et al (2000) Rapid evaluatimi of phenohc component profile and analysis of oleuropein aglycon in olive oil by atmospheric pressure chemical ionization-mass spectrometry (APCI-MS). J Agric Food Chem 48 1182-1185... 

Impellizzeri D et al (2011) The effects of oleuropein aglycone, an olive oil compound, in a mouse model of carrageenan-induced pleurisy. Clin Nutr 30 533-540... 

Impellizzeri D et al (2012) The effects of a polyphenol present in olive oil, oleuropein aglycone, in an experimental model of spinal cord injury in mice. Biochem Pharmacol 83 1413-1426... 

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