Of oxygen- and sulfur-containing

Cephachlor (35) became accessible when methods for the preparation of C-3 methylenecephalosporins became convenient. The allylic C-3-acetoxyl residue characteristic of the natural cephalosporins is activated toward displacement by a number of oxygen- and sulfur-containing nucleophiles. Molecules such as can therefore be prepared readily. Subsequent reduction with chromium(II) salts leads to the desired C-3... 

X-Ray studies of oxygen- and sulfur-containing ring systems 676... 

Nucleophilic Substitution of Oxygen- and Sulfur-Containing Groups... 

Heterocycles, 11, 1 The Photochemistry of Oxygen- and Sulfur-Containing Heterocycles, 33, 1 Photochemistry of Nitrogen-Containing Heterocycles,... 

Space restrictions mean that the reactivity of multiheteroatom systems or fused systems where both rings are heterocyclic cannot be covered in this section - the reader is referred to the relevant CHEC volumes. Space again dictates that the chemistries of oxygen- and sulfur-containing six-membered heterocycles, and the chemistry of monocyclic six-membered heterocycles with more than one heteroatom, are only briefly indicated alongside the description of pyridine/quinoline/isoquinoline chemistry, but especially where these are not shown by the pyridine prototypes, but again the reader should study the CHEC volumes for a full discussion. The inclusion of an extra heteroatom in a six-membered system exaggerates the effect of the first and so often it is possible to predict properties by extrapolation however, the same is not true for the five-membered systems, so these heterocycles with more than one heteroatom are considered in detail and separately. 

Rees, C. W., Smithen, C. E., The Reactions of Heterocyclic Compounds with Carbenes, 3,57. Reid, S. T., The Photochemistry of Heterocycles, 11,1 The Photochemistry of Oxygen- and Sulfur-Containing Heterocycles, 33, 1 Photochemistry of Nitrogert-Containing Heterocycles, 30, 239. 

Yamamoto, M., Kakinuma, M., Kohmoto, S., Yamada, K. Sommelet-Hauser rearrangement of oxygen- and sulfur-containing heteroaramatic sulfonium ylides. Bull. Chem. Soc. Jpn. 1989, 62, 958-960. 

S. A. Ryndina, A. V. Kadushkin, and V. G. Granik, Abstracts of Second International Conference on the Chemistry and Biological Activity of Oxygen- and Sulfur-Containing Heterocycles, Vol. 1, p. 392, IBS Press, Moscow (2003). 

E. J. Corey, Nobel Lecture, December 8, 1990, in The Chemistry and Biological Activity of Synthetic and Natural Compounds (2nd International Conference) . Chemistry and Biological Activity of Oxygen- and Sulfur-Containing Heterocycles, Keynote Lectures, p. 2, Moscow, Russia, October 14-17 (2003). 

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