O-Nitrobenzenes

The enamino ketone 49 has also been found to react with o-nitrobenzene-sulfenyl chloride to give the derivative 156, having the o-nitrophenylthio group substituted in the 2 position (93), i.e., the same position at which normal acylation with acid chlorides takes place. 

The reaction of ap- or o-nitrobenzene derivative with a nucleophilic reagent is generally first order with respect to each reactant and follows a bimolecular course according to Eq. (1). The reaction is then formally similar to the corresponding change at a saturated carbon ( Sj 2 ... 

Di-o-nitrophenyl disulfide was first prepared by the action of hydriodic acid on o-nitrobenzene sulfochloride.1 It has also been prepared by the reduction of o-nitrobenzene sulfinic acid with hydrogen bromide 2 by the reduction of ethyl-o-nitro-phenylsulfonacetate with ammonium sulfide 3 and by the deamination of 4,4,-diamino-2,2 -dinitrodiphenyldisulfide.4 The procedure given is the method of Blanksma5 as elaborated by Wohlfahrt.6... 

Protection of thiols. The r-butyl group has been of limited service for protection of thiols because removal has involved rather drastic treatment with liquid HF. r-Butyl thioethers can be cleaved by treatment with o-nitrobenzene-sulfenyl chloride in acetic acid at 25° to give S-o-nitrophenylsulfeny derivatives. These products are reduced to thiols with NaBH4, HSCH2C02H, or HOCH2CH2SH. 

Fig. I. Polymerization of DL-leucine carbonic anhydride, initiated by preformed polymer. , solvent, nitrobenzene, 45°C X, o-nitroanisole, 45° C O, nitrobenzene, 25.2° C A, o-nitroanisole, 25.0 C. [Reprinted from D. G. H. Ballard and C. H. Bamford Proc. Roy. See. A 223, 495 (1954) (Fig- 4)]...

Figure 4.7 Variation of parameter R as a function of the magnetic field, B(T). ( ) isooctane (A) polyethylene terephthalate (o) nitrobenzene in n-hexane.

CHLORONITROBENZENE see NFS525 CHLORO-m-NITROBENZENE see CJB250 m-CHLORONITROBENZENE see CJB250 CHLORO-o-NITROBENZENE see CJB750... 

Probably the most frequently used method of digestion incorporates the use of nitric and sulphuric acids. Kopp and Bandemar used this method and experienced 91 to 114% recovery of arsenic trioxide added to de-ionized water and 86 to 100% recovery of the compound added to river water. Evens and Bandemar recovered 87% of the arsenic trioxide added to eggs. By modifying the method by the addition of perchloric acid, and Caldwell and coworkers observed 80 to 90% arsenic recovery with o-nitrobenzene-arsonic acid, 85 to 94% with o-arsanilic acid and 76.7% with disodium methylarsenate. 

The starting material in this preparation is o-nitrobenzene sul-phinic acid, which may be prepared from o-nitroaniline by the diazo-reaction. Two grams of this acid in 20 c.c. of alcohol are added to 6 grams of mercuric chloride in a mixture of 20 c.c. of alcohol and 20 c.c. of water, and the resulting solution boiled for forty-five minutes. The precipitate is extracted with acetone, the solvent evaporated, and the residue crystallised from 95 per cent, alcohol, when faint yellow crystals, M.pt. 185° C. (corr.), are obtained. Yield 3 grams (78 per cent.). 

Attempts to prepare 2(2-hydroxy-3-vinylphenyl)2H-benzotriazole or 2(2-hydroxy-4-vinylphenyl)2H-benzotriazole failed. When 3-ethyl-phenol or 4-ethylphenol were allowed to condense with o-nitrobenzene-diazonium salts, the condensation did not occur in the 2 position but rather in the 4 position. As a consequence, after ring closure, bro-mination and debydrobromination, 2(4-hydroxy-2-vinylphenyl)2H-benzo-triazole (4-H2V) and 2(4-hydr oxy-3 - vinylphenyl) 2H-b enzotr iaz ole (4H3V) were obtained (30) instead of the desired 2H4V and 2H3V. 

Orthanilic acid was first made by the reduction of nitro-benzenesulfonic acid by ammonium sulfide.2 This reduction has also been carried out electrolytically, and by the use of iron or zinc.3 The acid has also been made by the rearrangement of phenylsulfamic acid,4 by the action of sodium hypobromite upon potassium 0-carbaminebenzenesulfonate,5 by the reduction of the mixed nitrobenzenesulfonic acids followed by separation of the isomers,6 by the action of methyl alcohol upon o-nitro-phenylsulfurchloride,7 by the action of acid upon diacetyl diphenylsulfamide,8 by the debromination of -bromoaniline-o-sulfonic acid,9 by the reduction of 1,2,6-aminothiophenolsulfonic acid,10 and by the hydrolysis and reduction of o-nitrobenzene-sulfonyl chloride, which was obtained from di-o-nitrophenyl-disulfide 1... 

CHLORO-o-NITROBENZENE (88-73-3) CSH4CINO2 Combustible solid (flash point 260°F/127°C). See chloronitrobenzenes. 1,1-CHLORONITROETHANE or 1-CHLORO-l-NITROETHANE (598-92-5) C2H4CINO2 Forms explosive mixture with air (flashpoint 133°F/56°C). Shock-, heat-, and friction sensitive explosive. Reacts violently with strong oxidizers, sodium hydroxide, potassium hydride. Contact with metal oxides can increase this material s explosive sensitivity. Quickly elevated temperatures can cause deflagration (explosive burning). 

CHLORO-o-NITROBENZENE (88-73-3) Combustible solid (flash point 255°F/124°C). A strong oxidizer. Violent reaction with reducing agents, combustible materials, powdered metals. Reacts with caustics (and may increase thermal sensitivity of this material), ammonia, amines. Attacks some plastics, rubber, and coatings. 

Figure 10. Real (in phase top) and imaginary (out of phase bottom) impedance as a function of applied interfacial potential at different BSA concentrations. Water 0.01 mol/L LiCl, BSA concentrations (ppm) 0.0 (curve 1, ) 0.5 (curve 2, ) 3.0 (curve 3, O). Nitrobenzene 0.01 mol/L TBATPB f = 5 Hz, t = 25.0 °C. (Reproduced with permission from reference 32. Copyright 1990...

Elimination of 3p-hydroxy and 1 la-hydroxy steroids. o-Nitrobenzene-sulfonyloxy groups undergo elimination in HMPT much more readily than p-toluenesulfonate groups. 

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