Nutritional disorder

Finally, an intriguing possible future therapy arises from a radical idea of Horrobin (2001) that schizophrenia is a nutritional disorder linked to a decreased intake of essential polyunsaturated fatty acids. Recent 31P-MRS studies have shown changes in plasma membrane phospholipids in the neocortex of unmedicated schizophrenics, which would have deleterious consequences on synaptic neurotransmission (Fukuzako, 2001). A clinical trial with the co6 fatty acid derivative ethyleicosa-pentaenoic acid (LAX-101) in patients who had been unresponsive to clozapine, reported that a daily dose of 2g LAX-101 gave a 26% improvement in symptoms over 12 weeks compared with 6% with placebo (Peet and Horrobin, 2001). Maybe in... 

Neurological disorders Nutritional disorders Obstetrical disorders Ophthalmoligical disorders... 

L.B. Willett and C.P. Hodgson of Ohio State University, in collaboration with the U.S. Department of Agriculture, are currently investigating reproductive, metabolic, and nutritional disorders following heptachlor exposure from contaminated food in cattle (FEDRIP 1990). These investigators will also determine the cellular alterations that can influence reproductive or other homeostatic mechanisms. 

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