Nucleophilic Substitution of Hydrogen SNH Reactions

Similarly, the C-5 adduct 123, obtained from reaction of 3-methylthio- 

4- triazine with phenylmagnesium bromide, was oxidized by potassium ferricyanide under alkaline conditions into 3-methylthio-5-phenyl- 

3-Methyl-6-phenyl-l,2,4-triazine reacts with hydrogen cyanide in the 

Similarly, when treated with bromine in aqueous solution, 4-amino-3-methylthio-l,2,4-triazin-5-one is converted into the corresponding 1,2,4- 

These inter- and intramolecular ring transformations of triazines have been reviewed extensively (83T2869 86CRV781 87MI1) thus, there is no need to dwell on this subject in more detail. We wish to mention here one particular example which will likely stimulate new investigations into the area of cycloaddition reactions. 

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