Nucleic acids relaxation behavior

The difference between the chemical behavior of low-molecular compounds and highly ordered macromolecular systems (proteins, and nucleic acids) is a consequence of the fact that in the latter case the relaxation to the equilibrium state after local perturbation of each individual macromolecule can take a rather long time. Thus, a macromolecule ensemble can be considered as the mixture of nonequilibrium molecules. 

Chi-Wan Chen and Jack S. Cohen introduce the application of - P NMR to DNA and RNA conformations. High-resolution P NMR of transfer ribonucleic acids and P studies on drug-nucleic acid complexes (prepared by the editor with Evelyn M. Goldfield) are then presented. Phillip A. Hart introduces phosphorus relaxation methods, which are shown to provide important information on the conformation and dynamics of nucleic acids and phosphoproteins. Thomas L. James delves further into relaxation behavior of solution-state nucleic acids, and Heisaburo Shindo completes this section by describing solid-state " P NMR of nucleic acids. 

Relaxation Behavior of Nucleic Acids Dynamics and Structure... 

---