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Nucleic acids functions

Flucytosine-resistant strains can develop very rapidly. These mutants may have a disturbed 5-FC-metabohsm, or a compensatory mechanism for the disturbed nucleic acid functions. No cytosine permease was found in a resistant Cyptococcus neoformans strain, whereas cytosine deaminase was absent in resistant C. albicans strains. A deficiency of uridine monophosphate pyrophosphorylase occurs frequently in resistant C. albicans strains (1). [Pg.256]

Dey S., Alpha Helical Peptide Nucleic Acids (Alpha PNAs) - Integration of Protein Structure and Nucleic Acid Function. PhD thesis. Case Western Reserve University, Cleveland, OH, January 2001. [Pg.220]

It is the sequence of the nucleotide bases in the DNA molecule that is fundamental to nucleic acid function. Hence the techniques that determine this sequence are extremely important in recombinant DNA technology. Two... [Pg.468]

Nguyen CV, Delzeit L, Cassell AM, Li J, Flan J, Meyyappan M (2002) Preparation of nucleic acid functionalized carbon nanotube Arrays. Nano Lett. 2 1079-1081. [Pg.48]

During the transfer of genetic information the interactions between DNA and the divalent ions Mg2+, Mn2 +, Co2 +, Cu2 Zn2+, Ni2+, Cr2+, Cd2+ and Pb2+, play an essential role in promoting and maintaining the nucleic acid functionalities. Some are recognized for their carcinogenicity... [Pg.111]

Inhibitors of nucleic acid function or synthesis (Chapter 32)... [Pg.298]

Inhibition of nucleic acid function prevents cell division and/or the synthesis of essential enzymes. Agents acting in this way include nalidixic acid and proflavin. [Pg.159]

As with all aspects of nucleic acid function, the synthesis of RNA molecules is a very complex process involving a variety of enzymes and associated proteins. Recall that RNA molecules are transcribed from the cell s genes. As RNA synthesis proceeds, the incorporation of ribonucleotides is catalyzed by RNA polymerase, sometimes referred to as DNA-dependent RNA polymerase. The reaction catalyzed by all RNA polymerases is... [Pg.639]

Emetine has been used in the treatment of amebiasis since 1912. It has now been shown that it blocks protein synthesis directly, and not as a result of altered nucleic acid function. ... [Pg.163]

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See also in sourсe #XX -- [ Pg.38 ]



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Acidic function

Acidic functionalities

Acidity functions

Correlation function, nucleic acids

Density function theory, nucleic acids

Functional Polymer Conjugates for Medicinal Nucleic Acid Delivery

Interference with Nucleic Acid Synthesis and Function

Nucleic acids functional groups

Nucleic acids structure and function

Overview of Nucleic Acid Function

Site-Specific Internal Functionalization of Nucleic Acids with Transition-Metal Ligands and Other Moieties

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