Nucleic acid antibody

If cellular localization of the antigen-antibody complex is not required, enzyme immunolabeling can be performed on cells adherent to a microtiter plate, and the color change resulting from the enzymatic reaction can be detected as a change in absorbance with an automatic plate reader (see Chapter 28). Biotinylation of antibodies and the use of the avidin-biotin complex has further extended the versatility and sensitivity of the enzymatic techniques (see Chapters 7 and 25-27). Most recently, the principles behind these techniques have been applied in combination with in situ hybridization techniques. Using nucleic acid-antibody complexes as probes, specific DNA or RNA sequences can be localized (see Chapters 46 9). 

The in situ technique that uses nucleic acid-antibody complexes as probes and nucleic acids as targets has been referred to as nucleic acid... 

Nucleic acid immunocytochemistry Nucleic acids, constitutive or foreign Nucleic acid antibody complexes Base sequence specific Localization of base-specific sequences on chromosomes, detection of human papilloma virus infection... 

DeHoratius RJ, Pillarisetty R, Messner RP, Talal N (1975) Anti-nucleic acid antibodies in systemic lupus erythematosus patients and their families. Incidence and correlation with lymphocytotoxic antibodies. J Clin Invest, 56 1149-1154. 

Probe technologies include those based on nucleic acids, antibody/antigen binding, and ligand/receptor interactions. 

Biosensors for bacterial detection involve biological recognition components such as presence of the biomarkers, nucleic acid, antibodies or aptamer attached on a transducer. However, in this chapter, bacterial nucleic acid will be described in detail [13]. 

Significant advances have been made in the design, formation, and characterization of polyurethane nanoparticles. Different approaches have been employed to synthesize polyurethane nanoparticles as carriers of imaging agents, as dmgs, or as copolymers to form different versatile matrices. The chemical reactivity and properties of these polymers make them suitable to bind peptides, nucleic acids, antibodies. 

Impedimetric Pathogens and food multiway biosensor Biological and environmental Enzyme based also equiped with microbes, nucleic acid, antibodies as recognising elements [279]... 

Steinberg, A. D., Pincus, T., Talal, N. The pathogenesis of autoimmunity in New Zealand mice. III. Factors influencing the formation of anti-nucleic acid antibodies. Immunology 20, 523-531 (1971). 

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