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Nuclear magnetic resonance spectroscopy ligand binding sites

Nuclear magnetic resonance (NMR) spectroscopy is a powerful tool that can provide the binding sites of Ugand-DNA interactions at the molecular level. A prerequisite for the examination of ligand-DNA complexes is assignment of all resonances in the NMR spectra of the free DNA and the ligand and of both components in the complex. [Pg.171]

The application of nuclear magnetic resonance (NMR) spectroscopy to the study of metal-ligand equilibria is growing rapidly. This technique can be used not only to determine stability constants but also to provide information on the structures of the complexes formed as well as the location of the binding sites on the ligand of the hydrogen and metal ions. ... [Pg.4549]


See other pages where Nuclear magnetic resonance spectroscopy ligand binding sites is mentioned: [Pg.86]    [Pg.92]    [Pg.735]    [Pg.18]    [Pg.2779]    [Pg.22]    [Pg.2]    [Pg.4]    [Pg.369]    [Pg.186]    [Pg.2]    [Pg.222]   
See also in sourсe #XX -- [ Pg.61 ]




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