Nonwoven fabrics wound dressing

An electrospinning process was used to fabricate silk fibroin (SF) nanofiber nonwovens for wound dressing applications. The electrospinning of regenerated silk fibroin (SF) was performed with formic acid as a spinning solvent For ciystallization, as-spun SF nanofiber nonwovens were chemically treated with an... 

Ohshima, Y., Nishino, K., Yonekura, Y., Kishimoto, S., Wakabayashi, S., 1987. Clinical application of chitin nonwoven fabric as wound dressing. European Journal of Plastic Surgery 10, 66—69. 

Mao N. Effect of fabric structure on the Uquid transport characteristics of nonwoven wound dressings [Ph.D. thesis]. University of Leeds 2000. 

Many standards for wound dressings have been introduced into ASTM and BS in recent years. Nonwoven wound dressings may need to comply with these standards together with standards for nonwoven fabrics when few standards have been established for nonwoven wound dressings. 

Muhammad and RusseU (2012) argues that composite structures provide excellent abrasion resistance, lint-free properties and efficiency besides effective barrier properties to many liquids, including blood, other body fluids, alcohol, water, etc. (Mogul, 2009). Nonwoven fabrics comprising of two or more fibrous layers are ubiquitous with applications in, but not limited to, scaffold for tissue engineering, wound dressings, surgical barrier fabrics and wipes. 

The purpose of antimicrobials in medical textiles such as wound dressings is to eithCT prevent infection from occurring or to contribute to the healing of infected wounds, and odour control is a subsidiary effect whereas, the inclusion of activated charcoal in wound dressings is specifically to manage odour. Activated charcoal cloth (ACC) is sandwiched/encapsulated between two layers of a polyamide nonwoven fabric. The ACC with silver has to be in close contact with the wound s surface in order for the silver ions to react with the bacteria causing the infection (Mcqueen, 2011). 

Yang, J. M., Lin, H. T. (2004). Properties of chitosan containing PP-g-AA-g-NIPAAm bigraft nonwoven fabric for wound dressing. Journal of Membrane Scierwe, 243(1—2), 1—7. 

Fihn-forming polymers can be coated on a textile substrate to enhance its performance. For example, chitosan can be coated on to nonwoven fabrics to produce non-woven wound dressings with enhanced properties. In this method, chitosan is first dissolved in an acidic solution before the nonwoven fabric is immersed, and a layer of chitosan is formed on the nonwoven fabric by using the immersion-precipitation phase-inversion method. The chitosan-coated nonwoven wound dressing can control water loss due to evaporation, promote fluid drainage, and inhibit the invasion of exogenous microorganisms. 

Many nonwoven structures used for absorbent wound dressings exhibit anisotropic fluid transmission characteristics in the vertical and lateral directions of the fabric structure. The orientation of fibers within these materials is the main factor affecting anisotropic fluid transmission, and can be manipulated to design desirable transport properties by using appropriate fabric porosity, fiber diameter, and orientation distribution. 

Electrospun mats have a larger specific surface area and smaller pore size compared to commercial nonwoven fabrics. They are of interest in a wide variety of applications, including semi-permeable membranes, nanocomposites, filters, protective clothing and biomedical applications such as wound dressings, tissue engineering scaffolds, and drug delivery systems. Recently, unidirectional-like nanofiber mats fabricated by control collector speed were reported and a high mechanical property was obtained. ... 

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