Nonsteroidal anti-inflammatory drugs blood pressure effects

Lefkowitz M The effects of nonsteroidal anti-inflammatory drugs blood pressures of patients with hypertensic i controlled by verapamil. (1995) 155,1049-54. 

The antihypertensive effect of beta-blockers can be impaired by the concurrent administration of some nonsteroidal anti-inflammatory drugs (NSAIDs), possibly because of inhibition of the synthesis of renal vasodilator prostaglandins. This interaction is probably common to all beta-blockers, but may not occur with aU NSAIDs for example, sulindac appears to affect blood pressure less than indometacin (405-407). 

Pope JE, Anderson JJ, Felson DT. A meta-analysis of the effects of nonsteroidal anti-inflammatory drugs on blood pressure. Arch Intern Med 1993 153(4) 477-84. 

Houston MC, Weir M, Gray J, Ginsberg D, Szeto C, Kaihlenen PM, Sugimoto D, Runde M, Lefkowitz M. The effects of nonsteroidal anti-inflammatory drugs on blood pressures of patients with hypertension controlled by verapamil. Arch Intern Med 1995 155(10) 1049-54. 

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