NMR Spectroscopy of Proteins

Inomata K, Ohno A, Tochio H, Isogai S, Tenno T, Nakase I, Takeuchi T, Futaki S, Ito Y, Hiroaki H, Shirakawa M (2009) High-resolution multi-dimensional NMR spectroscopy of proteins in human cells. Nature 458 106-109... 

Meyer B, Peters T (2003) NMR spectroscopy of proteins NMR spectroscopy techniques for screening and identifying ligand binding to protein receptors. Angew Chem Int lid Engl 42 864-890... 

According to these observations, the power of CLEAN algorithm was utilized in high-dimensional (3D and 4D) NMR spectroscopy of proteins (see Fig. 11), where sparse sampling has to be employed due to practical limitation on experiment time (see Sect. 9.4). 

Bermel W, Bertini I, Felli IC et al (2006) C-13-detected protonless NMR spectroscopy of proteins in solution. Prog Nucl Magn Reson Spectrosc 48 25 5... 

Recognition of Modified Cyclodextrins , p. 35 R 47 D.M. Hatch, J.O. Boles, Z. Li and L.A. Silks, Methods for the Synthesis of Heavy-Atom Derivatized Amino Acids Useful Probes for X-Ray Crystallography, Vibrational, and NMR Spectroscopy of Proteins , p. 47... 

Ballard, L. Jonas, J. High-pressure NMR Spectroscopy of Proteins. In Biolo cal Systems Under Extreme Conditions-, Taniguchi, Y., Stanley, H. E., Ludwig, H., Eds. Springer Berlin, 2002 pp 75-100. 

K. W. Zihn, Sensitive high resolution inverse detection NMR spectroscopy of proteins in the sohd state, J. Am. Chem. Soc. 125 (2003) 15831—15836. 

Solid-State NMR spectroscopy of protein complexes has been reviewed by Sun el al The article considers protein-protein interactions, which often result in the formation of protein assemblies that are large in size, insoluble, and difficult to crystallize, and therefore are challenging to study by structural biology techniques, such as single crystal X-ray diffraction and solution NMR spectroscopy. Solid-state NMR spectroscopy is shown to be... 

Solid-State NMR Spectroscopy of Proteins Stanley J. Opella... 

H. Mueller, M. Etzkorn and H. Heise, Solid-State NMR Spectroscopy of Proteins, in Modem NMR Methodology, ed. H. Heise, Topics in Current Chemistry, Springer, 2013, vol. 335, p. 121. 

S. Sun, Solid-State NMR Spectroscopy of Protein Complexes, in Protein NMR Techniques, ed. A. Shekhtman and D. S. Burz, Methods in Molecular Biology, Springer, New York, NY, United States, 2012, vol. 831, p. 303. 

Jonas J and Jonas A (1994) High pressure NMR spectroscopy of proteins and membranes. Armual Reviews In Biophysical and Blomolecular Structure 23 287-318. 

In the current chapter we focus on recent techniques and applications in MAS-NMR spectroscopy of proteins and biomolecules. 

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