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NMDA receptor antagonists analgesics

Dickenson, AH (1990) A cure for wind-up NMDA receptor antagonists as potential analgesics. Trends Pharm. Sci. 11 307-309. [Pg.224]

Chizh BA, Headley PM, Tzschentke TM (2001) NMDA receptor antagonists as analgesics focus on the NR2B subtype. Trends Pharmacol Sci 22 636-642 Choi DW (1995) Calcium stiU center-stage in hypoxic-ischemic neuronal death. Trends Neurosci 18 58-60... [Pg.287]

Chizh, B. A., Headley, P. M., Tzschentke, T. M. NMDA receptor antagonists as analgesics focus on the NR2b subtype, Trends Pharmacol. Sci., 2001, 22, 637-643. [Pg.415]

Hehny SA, Bah A. The effect of the preemptive use of the NMDA receptor antagonist dextromethorphan on postoperative analgesic requirements. Anesth Analg 2001 92(3) 739-44. [Pg.1091]

Caruso FS, Goldblum R. Dextromethorphan, an NMDA receptor antagonist, enhances the analgesic properties of morphine. Inflammopharmacology 2000 8 161-73. [Pg.1092]

Category Analgesic, narcotic NMDA receptor antagonist... [Pg.174]

The NMDA receptor antagonists, LY274614 and MK-801, and the nitric oxide synthase inhibitor, NG-nitro-L-arginine, attenuate analgesic tolerance to the mu-opioid morphinebut not to kappa opioids... [Pg.120]

Trade Names Anesject , Brevinaze , Keiran , Keta , Ketaject , Ketalar , Ketalin , Ketamax Drug Class NMDA receptor antagonist, centralacting analgesic... [Pg.316]

Orphenadrine does not cause direct skeletal muscle relaxation. Proposed mechanisms of action of orphen-adrine include HI receptor antagonist [5,13,14], NMDA receptor antagonist and muscarinic antagonist [5,13] activities. Recent evidence also demonstrates orphenadrine has a sodium channel blockade effect which has been attributed to the analgesic char-acterisics of the drug (as well as proarrhythmic and proconvulsive effects) [13]. [Pg.361]

Flupirtine is both a nonspecific antagonist NMDA and an agonist of opioid receptors. This analgesic is prescribed for migraine. Neuroprotector effects in neurodegenerative diseases (Alzheimer and prion diseases) are being investigatived. ... [Pg.306]

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See also in sourсe #XX -- [ Pg.6 , Pg.449 ]



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